Functional micro- and nanostructured materials

 

Group Leader: prof. Ing. Petr Slepička, Ph.D.

                            doc. Ing. Nikola Slepičková Kasálková, Ph.D.

 

Researcher: Ing. Iva Labíková, Ph.D.

 Ph.D. Students: Ing. Bára Frýdlová                                 Students: bc. Tatiana Maria Náhluková

                             Ing. Šárka Havlíčková                                              bc. Klára Zahradníková

                             Ing. Matěj Budina

 

 Main research areas of the group

  • Surface modification and functionalization of materials
    Plasma, laser, and chemical modification of polymers and biopolymers; thin-film deposition and control of physicochemical surface properties.
  • Micro- and nanostructured materials
    Preparation of functional micro- and nanostructures, periodic structures (LIPSS), porous and hierarchical surfaces, metal and carbon nanostructures, and polymer nanocomposites.
  • Biomaterials and tissue engineering
    Development of polymeric, biopolymeric, and composite materials, hydrogels, and structured substrates for regenerative medicine and tissue engineering.
  • Biointeractions and antibacterial materials
    Study of the relationship between surface chemical composition/morphology and biological response—specifically cell adhesion and proliferation, cytocompatibility, and antibacterial activity.
  • Characterization of surfaces and nanostructures
    Comprehensive study of surface morphology and roughness, chemical composition, wettability, and other properties of prepared materials using advanced microscopy and surface analysis methods.

 

prof. Ing. Petr Slepička, Ph.D.

  • Laser and plasma modification of polymers – targeted changes to chemical composition, morphology, roughness, and surface wettability.
  • Laser-induced periodic surface structures (LIPSS) – fabrication of regular nanostructures and investigation of their physicochemical and biological properties.
  • Metal nanostructures and thin films – metal deposition on solid substrates, subsequent reorganization and study of metal-polymer interactions, and laser-induced dewetting.
  • Biopolymer micro- and nanostructures – structuring of biocompatible polymers and fabrication of hierarchical or porous structures, including "honeycomb" structures.
  • Materials for tissue engineering – study of the influence of surface chemistry and topography on cell adhesion, proliferation, and orientation, and the development of materials suitable for contact with the biological environment.
  • Antibacterial surfaces – combination of polymer substrates and metal nanostructures to achieve antibacterial activity while maintaining suitable cytocompatibility.
  • Carbon nanostructures and composites – fabrication of novel carbon structures and combination of carbon with metals and polymer materials.
  • Characterization of surfaces and nanostructures – primarily AFM, SEM, and FIB-SEM, complemented by the study of physicochemical surface properties.
 
 

doc. Ing. Nikola Slepičková Kasálková, Ph.D.

  • Biomaterials for tissue engineering – development of polymeric and composite materials designed for contact with the biological environment, including biodegradable and biostable substrates and materials for applications such as vascular and skin tissue engineering.
  • Hydrogels and polymer carriers – preparation and characterization of hydrogel systems for medical applications and tissue engineering.
  • Surface modification of polymers – use of plasma, lasers, thin-film deposition (noble metals, carbon, etc.), chemical grafting, and other techniques to selectively alter surface chemistry, wettability, and morphology.
  • Micro- and nanostructured biomaterials – preparation of surfaces with controlled topography/morphology and study of the influence of micro- and nanostructures on material-cell interactions.
  • Biocompatibility and cell-material interactions – study of cytocompatibility, cell adhesion, and other biological interactions in relation to material chemical composition and structure.
  • Antibacterial materials – development of surfaces combining a favorable biological response with antibacterial properties, utilizing methods such as metal or carbon nanostructures.
  • Carbon materials and nanostructures – preparation and characterization of specific forms of carbon and carbon nanostructures (e.g., Q-carbon).
  • Characterization of surface properties – study of wettability, morphology, chemical composition, and other surface properties, and the investigation of their relationship to the material's resulting biological function.